Amy Brann: How to Achieve Sustainable High Performance by Working With the Brain

Amy Brann explores one of the most pressing questions for today’s leaders: how to unlock sustainable high performance without exhausting people in the process. She argues that many organisations still rely on performance models designed for a very different era—approaches that no longer match how the human brain actually functions at work.

Drawing on more than two decades of neuroscience and behavioural science research, Brann introduces the Whole Brain Potential™ framework, a practical, science-based approach that helps individuals and teams work in alignment with how the brain is designed to operate. Rather than pushing harder or increasing pressure, the framework focuses on enabling people to access the capabilities they already have but may not be fully using.

The keynote highlights how performance improves when individuals feel empowered, mentally supported, and confident in their ability to contribute meaningfully. Participants learn how to take control of their own effectiveness while avoiding the common trap of burnout. The emphasis is on building habits that strengthen cognitive capacity, focus, and engagement in a sustainable way.

Audiences leave with a deeper appreciation of human brain potential, a clear structure they can apply to daily work, and evidence-based practices that support both stronger results and healthier, more fulfilled people. The message is clear: high performance and wellbeing are not opposites—they reinforce each other when organisations work with the brain, not against it.